Profile

Daiki Kumakura · 熊倉大騎

I am a mathematical biologist and a bioinformatics researcher in the pharmaceutical industry. I received my Ph.D. in Life Science from Hokkaido University in March 2025.

Expertise

My expertise is in mathematical modeling and quantitative data analysis. I work on how dynamic systems can be represented, what can be learned from observations, and how assumptions affect the conclusions. My current interests include pharmacometrics and model-informed drug development. In personal technical notes, I apply population PK, PK/PD, exposure–response and tumor-dynamics models to public data and simulations to examine dose and regimen questions.

Mathematical modeling

Dynamical systems and differential equations, with an emphasis on models that capture the essential structure of a problem. I use models to connect mechanisms with observed patterns and to examine competing explanations.

Statistical inference and uncertainty

Parameter estimation, time-series analysis and model evaluation. I focus on what the available data can support, where uncertainty remains, and how conclusions depend on modeling assumptions.

Interactions and causal reasoning

Analysis of interactions in dynamic systems, including CCM (Convergent Cross Mapping). I am interested in distinguishing predictive relationships from causal interpretations and making the assumptions behind each analysis explicit.

Appointments

2025-04–Bioinformatics researcher in the pharmaceutical industry
2022-04–2025-03Junior Research Associate, RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS)

Education

2022-04–2025-03-25Ph.D. in Life Science, Graduate School of Life Science, Hokkaido University
2020-04–2022-03Master’s degree, Graduate School of Life Science, Hokkaido University
2016-04–2020-03Bachelor’s degree in Fisheries Science, Department of Aquaculture Life Science, School of Fisheries Sciences, Hokkaido University