Inavolisib renal dosing: AUC, peaks and troughs
Published inavolisib PK separates renal dose adjustment, AUC matching and concentration shape without predicting clinical benefit.
Daiki Kumakura
I am a mathematical biologist and a bioinformatics researcher in the pharmaceutical industry. I received my Ph.D. in Life Science from Hokkaido University in March 2025.
I study biological dynamics using mathematical models and data analysis, with an interest in pharmacometrics and systems biology.
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Recent writing
Can an AI agent do a PK/PD analysis? Re-running a warfarin analysis with a public skill library
Four AI-agent warfarin PK/PD analyses expose hidden implementation and refitting failures despite similar headline results.
Can blood proteins read immune aging? From cell states to proxy measurements
Cell recovery and protein-proxy errors answer different questions. Two numerical examples examine an immune-aging study without claiming clinical validation.