How many of Carbon-A's 566 million gene candidates are real?
An audit of the October 18 Carbon-A snapshot distinguishes assembly redundancy, confidence, RefSeq agreement and missing predictions.
Daiki Kumakura
I am a mathematical biologist and a bioinformatics researcher in the pharmaceutical industry. I received my Ph.D. in Life Science from Hokkaido University in March 2025.
I study biological dynamics using mathematical models and data analysis, with an interest in pharmacometrics and systems biology.
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Recent writing
Proteome-guided degrader design: separating target degradation from mitochondrial effects
Public proteomics and respiratory-chain data reveal the gains and limits of redesigning an androgen-receptor degrader.
Amivantamab IV/SC PK bridging: is matching AUC sufficient?
Conditional numerical simulations of the public EMA model distinguish systemic input, finite-window AUC and predose concentration. Reference profiles are contrasted with observed PALOMA-3 geometric mean ratios without claiming clinical noninferiority, population reproduction or individual switching predictions.